Nurofen For Children 3m+ Orange (150ml). The active ingredient (which makes this medicine work) is ibuprofen which is a non-steroidal-antiinflammatory (NSAID) painkiller.. Ibuprofen is used as an analgesic (painkiller) for the relief of teething and toothache pain, earache, headache, muscular minor aches and sprains, sore throats and cold and flu symptoms.. Nurofen for Children Cold & Flu & Pain also reduces a high temperature (fever).