Nylabone Puppy Bone Souper for Large Teething Puppies.. Puppybone is made from inert thermopolymer to which calcium has been added during the moulding process.. Puppybone is strong and durable but the addition of the calcium, being a natural material, makes the product a little softer than Gumabone and is suitable for use by very young dogs whose jaws and adult teeth are still developing. Remember that as he grows he will need to progress to a larger chew Chicken Flavour.. Souper 8 inches approx for puppies up to 50lbs.